Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.
Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is a common dietary component that has histone deacetylase inhibition activity and exciting potential in cancer prevention.The mechanisms by which SFN imparts its chemopreventive properties are of considerable interest and little is known of its preventive potential for breast c